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DBCO-Propionyl-Val-Cit-PAB(m-PEG8)-MMAE Size:25mg amine-containing groups

SKU 1263364888
4.1
USD445.00 USD480.00

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Description

amine-containing groups

Product Name DOTA-tris(t-Bu)ester-octyne Synonyms CAS Number n/a Related CAS Molecular Formula C36H65N5O7 Molecular Weight 679

48 Purity (HPLC) >= 95% Physical Appearance Dark Blue Solid Optical Properties Abs/Em Maxima: 650/660nm Solubility DMSO

Product Name Phthalimidinoglutarimide-C5-Br Synonyms Phthalimidinoglutarimide-4'-C5-Br CAS Number n/a Related CAS Molecular Formula C18H21BrN2O3 Molecular Weight 393

Product Name dCeMM1 Synonyms CAS Number 118719-16-7 Related CAS Molecular Formula C14H13BrN2O3S Molecular Weight 369

DBCO-Propionyl-Val-Cit-PAB(m-PEG8)-MMAE Size:25mg amine-containing groupsSOLU KNEX cleavable linker features a Val Cit dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing

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